Minimal important difference in opioid consumption based on adverse event reduction—A study protocol
Study context
- Population
- Patients undergoing total hip and knee arthroplasty (PANSAID, DEX2TKA, Pain Map)
- Planned comparison
- Opioid consumption in patients with no vs mildest degree of opioid-related adverse effects
- Primary endpoint
- Hodges-Lehmann median difference in opioid consumption between patients with no opioid-related adverse effects and those with the mildest degree of ≥1 opioid-related adverse effect
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Minimal important difference in opioid consumption based on adverse event reduction—A study protocol. Acta Anaesthesiol Scand. Published 9 December 2022. doi:10. 1111/ aas. 14175
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