Sepsis & infection

Mitral annular plane systolic excursion for assessing left ventricular systolic dysfunction in patients with septic shock

BJA OpenPublished Diagnostic accuracy study

Authors' conclusion

Septal MAPSE is easily measured at the bedside and might help clinicians to detect left ventricular systolic dysfunction early-especially when myocardial strain measurements are not feasible.

Study context

Population
Patients with septic shock
Participants
71 patients
Comparison
Septal mitral annular plane systolic excursion (MAPSE) for LV systolic dysfunction
  • Septal MAPSE ≥1.2 cmn = 18
  • Septal MAPSE <1.2 cmn = 53
Outcome
LV systolic dysfunction (LVEF <50%, LVLS greater than −17%, or both)
Methodological detailsconditional inference tree
  • Conditional inference tree

Performance

As reported in the abstract

Test or modelValueNormal left ventricular ejection fraction (LVEF) predictedLV systolic dysfunction with impaired LVLS predictedPreserved LVEF
Septal MAPSE ≥1.2 cm94%17/18
Septal MAPSE <1.2 cm87%46/5332/53 (60%)

Value

Septal MAPSE ≥1.2 cm94%
Septal MAPSE <1.2 cm87%

Normal left ventricular ejection fraction (LVEF) predicted

Septal MAPSE ≥1.2 cm17/18
Septal MAPSE <1.2 cm— not stated in the abstract

LV systolic dysfunction with impaired LVLS predicted

Septal MAPSE ≥1.2 cm— not stated in the abstract
Septal MAPSE <1.2 cm46/53

Preserved LVEF

Septal MAPSE ≥1.2 cm— not stated in the abstract
Septal MAPSE <1.2 cm32/53 (60%)
Agreement between septal MAPSE and LV systolic dysfunction
0.525 [0.299-0.751]

Original publication

Mitral annular plane systolic excursion for assessing left ventricular systolic dysfunction in patients with septic shock. BJA Open. Published 12 August 2023. doi:10.1016/j.bjao.2023.100220

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