Mixing short‐ and long‐acting local anaesthetics in peripheral nerve blocks: Protocol for a systematic review and meta‐analysis
Study context
- Population
- Patients receiving peripheral nerve blocks
- Planned comparison
- Mixed short- and long-acting local anaesthetics in peripheral nerve blocks
- Primary endpoint
- Duration of block analgesia
Methodological detailstrial sequential analysis, subgroup and sensitivity analyses, GRADE, Risk of bias and publication bias assessed, Secondary outcomes: block onset time, sensory and motor block duration; exploratory: postoperative pain scores, cumulative 24-h opioid consumption, prevalence of serious adverse events
- Trial sequential analysis
- Subgroup and sensitivity analyses
- GRADE
- Risk of bias and publication bias assessed
- Secondary outcomes: block onset time, sensory and motor block duration; exploratory: postoperative pain scores, cumulative 24-h opioid consumption, prevalence of serious adverse events
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Mixing short‐ and long‐acting local anaesthetics in peripheral nerve blocks: Protocol for a systematic review and meta‐analysis. Acta Anaesthesiol Scand. Published 10 November 2023. doi:10.
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