Respiratory failure & ventilation
Mobile Critical Care Recovery Program for Survivors of Acute Respiratory Failure: A Randomized Clinical Trial
Authors' conclusion
Findings from this randomized clinical trial indicated that a nurse-led 12-month comprehensive interdisciplinary care intervention did not significantly improve the QOL of ARF survivors after ICU hospitalization.
Study context
- Population
- Acute Respiratory Failure (ARF) survivors admitted to ICU services of 4 Indiana hospitalsITT analysis
- Participants
- 466 survivors
- Comparison
- 12-month nurse-led collaborative care vs telephone-based control
- Mobile Critical Care Recovery Program (m-CCRP)n = 233
- Controln = 233reference
- Primary endpoint
- QOL by SF-36 physical component summary (PCS) and mental component summary (MCS), 0-100, higher = better
- Follow-up
- 12 months
Methodological detailsconcealed outcome assessments, multicentre (4 Indiana hospitals), Conducted March 1, 2017, to April 30, 2022
- Concealed outcome assessments
- Multicentre (4 Indiana hospitals)
- Conducted March 1, 2017, to April 30, 2022
Primary result
As reported in the abstract
QOL (SF-36 PCS and MCS), change from baseline
Each group vs controlEstimate (95% CI)
m-CCRP
estimated difference in change from baseline (SF-36 PCS) 1.61(−1.06 to 4.29)
m-CCRP
estimated difference in change from baseline (SF-36 MCS) −2.50(−5.29 to 0.30)
Further findings
Mortality · 12 months · not statistically significantly lower
P = 0.05
Safety
Hospitalization · higher in m-CCRP
P = 0.04
Original publication
Mobile Critical Care Recovery Program for Survivors of Acute Respiratory Failure: A Randomized Clinical Trial. JAMA Netw Open. Published 2 January 2024. doi:10.
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