Respiratory failure & ventilation

The impact of an intensive care telemedicine program on weaning from invasive ventilation: a secondary analysis of the ERIC trial

Crit CarePublished Secondary analysis of the ERIC randomised trial

Authors' conclusion

Although ICU telemedicine did not improve the weaning success rate, our findings indicate that it facilitates the exploitation of existing weaning potential by ensuring more frequent SBTs and thereby shortening ventilation duration of successfully weaned patients.

Study context

Population
ICU patients on invasive mechanical ventilation for ≥2 consecutive days with ≥1 spontaneous breathing trial (SBT), Berlin, Germany308 analysed
Participants
1,463 patients
Comparison
Complex telemedicine intervention vs control condition
  • Interventionn = 253
  • Controln = 55reference
Primary endpoint
Weaning process: SBTs (% of patient days)
Methodological detailsstepped-wedge, cluster-randomized, 10 clusters of ICUs
  • Stepped-wedge
  • Cluster-randomized
  • 10 clusters of ICUs

Primary result

As reported in the abstract

SBTs (% of patient days)

P < 0.001

Further findings

Duration of invasive mechanical ventilation, successfully weaned patients · significantly shorter in the intervention group

P = 0.031

OutcomeOR (95% CI)P value
Weaning failure (multivariable regression)Intervention not associated with weaning success1.45 (0.71–2.95)P = 0.302
Outcomeβ (CI)P value
Time between first SBT and successful weaning (multivariable regression)Shorter time with the intervention0.56 (0.32–0.98)P = 0.042

Weaning classification

No difference between the groups
P = 0.21

Weaning success rate

No difference between the groups (28% vs 36%)
P = 0.32

Time from first SBT to successful weaning

No difference between the groups (2 [IQR 1, 5] vs 4 [IQR 1, 13] days)
P = 0.12

Original publication

The impact of an intensive care telemedicine program on weaning from invasive ventilation: a secondary analysis of the ERIC trial. Crit Care. Published 7 August 2026. doi:10.1186/s13054-026-06234-z

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