ICU sedation, delirium & recovery
Determinants of Subjective Mental and Functional Health of Critical Illness Survivors: Comparing Pre-ICU and Post-ICU Status
Authors' conclusion
The majority of ICU survivors did not experience substantial changes in their subjective health status, but patients with long ICU stays were prone to subjective mental and functional health decline.
Study context
- Population
- ICU survivors, 10 ICU clusters in Germany1,478 follow-up assessments
- Participants
- 855 survivors
- Comparison
- Pre-ICU vs post-ICU subjective mental and functional health
- Primary endpoint
- Decline or improvement (≥3 points) in subjective mental and functional/physical health (VAS 0 worst–10 best), post-ICU vs pre-ICU
- Follow-up
- 3 and 6 months after ICU discharge
Methodological detailsmulticentre
- Multicentre
Primary result
As reported in the abstract
Change in subjective health ≥3 points · first follow-up
- Mental health decline
- 20% (n = 165/841)
- Functional health decline
- 30% (n = 256/849)
- Mental health improvement
- 16% (n = 133/841)
- Functional health improvement
- 16% (n = 137/849)
- Mental health unchanged
- 65% (n = 543/841)
- Functional health unchanged
- 54% (n = 456/849)
Further findings
| Outcome | Adjusted OR (95% CI) | P value | |
|---|---|---|---|
| Determinants of mental health decline (multivariable mixed-effects logistic regression)ICU LOS (per ICU day) | 1.04 (1.00–1.09) | P = 0.038 | |
| Determinants of mental health decline (multivariable mixed-effects logistic regression)Age (per year) | 0.98 (0.96–0.99) | P = 0.003 | |
| Determinants of functional health decline (multivariable mixed-effects logistic regression)ICU LOS (per ICU day) | 1.06 (1.01–1.12) | P = 0.026 | |
| Determinants of functional health decline (multivariable mixed-effects logistic regression)Time after discharge (per month) | 0.86 (0.79–0.94) | P = 0.001 | |
| 0.512Adjusted odds ratio (log scale) |
Original publication
Determinants of Subjective Mental and Functional Health of Critical Illness Survivors: Comparing Pre-ICU and Post-ICU Status. Crit Care Med. Published 8 January 2024. doi:10.
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