Modified versus conventional intubation and early versus delayed oral intake in thyroid surgery: a 2 × 2 factorial randomized controlled trial
Authors' conclusion
While overall recovery scores remained unchanged, both the modified EMG intubation protocol and early oral intake improved perioperative comfort and procedural efficiency.
Study context
- Population
- Adults scheduled for elective thyroid surgery with intraoperative neural monitoring, Peking Union Medical College Hospital, Beijing, China (April 2023 - February 2024)
- Participants
- 200 adults
- Comparison
- Modified vs conventional electromyographic (EMG) intubation protocol, and early (within 1 h post-extubation) vs delayed (6 h postoperatively) oral intake
- Primary endpoint
- QoR-15 score
- Follow-up
- POD 1
Methodological detailssingle-centre, prospective, 2 × 2 factorial
- Single-centre
- Prospective
- 2 × 2 factorial
Primary result
As reported in the abstract
- No significant difference between groups
Secondary outcomes
| Outcome | Median difference (s) |
|---|---|
| Intubation timeModified vs Conventional | - 13.0 |
Sore throat severity
- Reduced with the modified intubation protocol
Thirst and hunger
- Alleviated with early oral intake (EOI)
LOS and patient satisfaction
- No group differences observed
Original publication
Modified versus conventional intubation and early versus delayed oral intake in thyroid surgery: a 2 × 2 factorial randomized controlled trial. Perioper Med (Lond). Published 9 October 2025. doi:10. 1186/ s13741-025-00594-w
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