Airway management

Modified versus conventional intubation and early versus delayed oral intake in thyroid surgery: a 2 × 2 factorial randomized controlled trial

Perioper Med (Lond)Published Randomised controlled trial

Authors' conclusion

While overall recovery scores remained unchanged, both the modified EMG intubation protocol and early oral intake improved perioperative comfort and procedural efficiency.

Study context

Population
Adults scheduled for elective thyroid surgery with intraoperative neural monitoring, Peking Union Medical College Hospital, Beijing, China (April 2023 - February 2024)
Participants
200 adults
Comparison
Modified vs conventional electromyographic (EMG) intubation protocol, and early (within 1 h post-extubation) vs delayed (6 h postoperatively) oral intake
Primary endpoint
QoR-15 score
Follow-up
POD 1
Methodological detailssingle-centre, prospective, 2 × 2 factorial
  • Single-centre
  • Prospective
  • 2 × 2 factorial

Primary result

As reported in the abstract

  • No significant difference between groups

Secondary outcomes

OutcomeMedian difference (s)
Intubation timeModified vs Conventional- 13.0

Sore throat severity

Reduced with the modified intubation protocol

Thirst and hunger

Alleviated with early oral intake (EOI)

LOS and patient satisfaction

No group differences observed

Original publication

Modified versus conventional intubation and early versus delayed oral intake in thyroid surgery: a 2 × 2 factorial randomized controlled trial. Perioper Med (Lond). Published 9 October 2025. doi:10.1186/s13741-025-00594-w

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