Monocyte Distribution Width as a Diagnostic Marker for Infection: A Systematic Review and Meta-analysis
Authors' conclusion
MDW exhibited good diagnostic performance for sepsis and COVID-19.
Study context
- Population
- Patients evaluated for infectious disease outcomes (mainly sepsis and COVID-19) across care settings29 studies
- Outcome
- Diagnostic performance of MDW across multiple infectious disease outcomes
Methodological detailslinear mixed-effects models
- Linear mixed-effects models
Pooled result
As reported in the abstract
Diagnostic performance of MDW for sepsis (19 studies) and COVID-19 (six studies), pooled
- Sepsis: pooled AUC
- 0.74 to 0.94
- Sepsis: mean sensitivity
- 0.69 to 0.79
- Sepsis: mean specificity
- 0.57 to 0.86
- COVID-19: pooled AUC
- 0.76
- COVID-19: mean sensitivity
- 0.79
- COVID-19: mean specificity
- 0.59
Further pooled results
| Outcome | Values |
|---|---|
| COVID-19Six studies | MDW pooled AUC 0.76 · mean sensitivity 0.79 · mean specificity 0.59 |
Original publication
Monocyte Distribution Width as a Diagnostic Marker for Infection: A Systematic Review and Meta-analysis. Chest. Published 18 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →