Mortality in Patients with Obesity and Acute Respiratory Distress Syndrome Receiving Extracorporeal Membrane Oxygenation: The Multicenter ECMObesity Study
Main finding · ICU mortalityResult — go to the resultOdds ratio 0.63 95% CI 0.43–0.93Authors' conclusion
Among patients receiving ECMO for ARDS, those with obesity had lower ICU mortality than patients without obesity in multivariable and propensity score matching analyses.
Study context
- Population
- Patients with acute respiratory distress syndrome (ARDS) receiving extracorporeal membrane oxygenation (ECMO)
- Participants
- 790 patients
- Exposure
- Obesity vs no obesity
- Obesityn = 320
- Outcome
- ICU mortality
Methodological detailsinternational, multicentre, multivariable logistic regression, propensity-score matched
- International
- Multicentre
- Multivariable logistic regression
- Propensity-score matched
Main finding
As reported in the abstract
Odds ratio
0.63
95% CI 0.43–0.93
P = 0.018
By group
Obesity vs No obesity
OR 0.63 (95% CI 0.43–0.93); P = 0.018
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| ICU mortality per BMI as continuous variableMultivariable regression | 0.97 (0.95–1.00) | P = 0.023 | |
| 0.512Odds ratio (log scale) |
ICU death (propensity score matched)
P = 0.007
- ICU death (propensity score matched): 199 patients with obesity matched to 199 without
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Mortality in Patients with Obesity and Acute Respiratory Distress Syndrome Receiving Extracorporeal Membrane Oxygenation: The Multicenter ECMObesity Study. Am J Respir Crit Care Med. Published 15 September 2023. doi:10.
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