Mortality of cancer patients with septic shock: A nation-based cohort analysis of 77,888 patients
Authors' conclusion
In septic shock patients, solid cancer and hematological cancer were associated with increased 90-day mortality compared with noncancer patients.
Study context
- Population
- Adults with septic shock, French national hospitalization database, 2017–2018
- Participants
- 77,888 adults
- Exposure
- Solid cancer or hematological cancer vs noncancer
- Noncancern = 52,061reference
- Solid cancern = 19,329
- Hematological cancern = 6,498
- Outcome
- Hospital mortality rate in patients with solid cancer and hematological cancer
- Follow-up
- 90 days
Methodological detailsnationwide hospitalization database, multivariable analysis
- Nationwide hospitalization database
- Multivariable analysis
Main finding
As reported in the abstract
90-day mortality
Each group vs noncancerAdjusted hazard ratio (CI)
Solid cancer
1.55(1.51–1.59)
Hematological cancer
1.59(1.53–1.65)
Observational data: associations, not effects.
Secondary outcomes
- Risk factors for 90-day mortality included both hematological and solid cancers
Original publication
Mortality of cancer patients with septic shock: A nation-based cohort analysis of 77,888 patients. Anaesth Crit Care Pain Med. Published 26 May 2025. doi:10. 1016/ j. accpm. 2025. 101557
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