Infections Acquired in the ICU Among Cancer and Other Immunosuppressed Patients: A Nationwide Cohort Study
Authors' conclusion
Patients with hematological malignancies and other immunosuppressive conditions face a significantly higher risk of ICU-AIs.
Study context
- Population
- Adult patients admitted to 50 ICUs in Brazil between October 2019 and December 2021 with an ICU stay exceeding 48 hours and no infections diagnosed within the first 48 hoursadult patients, 50 participating ICUs
- Participants
- 38,126 patients
- Exposure
- Immunosuppression diagnostic categories vs nonimmunosuppressed patients
- Outcome
- Incidence of the first ICU-AI during the ICU stay
- Follow-up
- During the ICU stay
Methodological detailscompeting-risk analysis, multivariable
- Competing-risk analysis
- Multivariable
Main finding
As reported in the abstract
Each group vs non-immunosuppressed patientsSubdistribution hazard ratio (95% CI)
Hematological malignancies
1.64(1.01–2.65)
Other immunosuppressive conditions
1.61(1.02–2.54)
Solid malignancy
0.88(0.68–1.14)
Observational data: associations, not effects.
Original publication
Infections Acquired in the ICU Among Cancer and Other Immunosuppressed Patients: A Nationwide Cohort Study. Crit Care Med. Published 19 October 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →