Cardiothoracic & vascular anesthesia
Multimodal Brain Monitoring in Cardiac Surgery and Postoperative Patient Outcomes
Authors' conclusion
Multimodal neuromonitoring during cardiac surgery identified high-risk patients, particularly those with concurrent desaturation and burst suppression, who had significantly worse outcomes.
Study context
- Population
- Adults undergoing cardiac surgery with cardiopulmonary bypass (CPB), university-affiliated cardiology center175 with transcranial Doppler (TCD) monitoring
- Participants
- 374 adults
- Exposure
- Cerebral states by rSO₂ desaturation and PSI <25
- Outcome
- Outcomes by cerebral state (4 states)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- State 4 (desaturation and PSI <25): higher EuroSCORE II, more comorbidities, longer CPB/aortic clamping times, worse postoperative outcomes incl. extended intensive care unit (ICU) and hospital stays
- Multivariable models confirmed associations with adverse outcomes, some effects attenuated after adjustment
Observational data: associations, not effects.
Further findings
Outcomes by cerebral state incl. HITS severity (TCD subsample, 8 groups)
- Moderate-to-severe HITS with desaturation and PSI <25: poorest outcomes, e.g. prolonged hospitalization and difficult CPB separation
Original publication
Multimodal Brain Monitoring in Cardiac Surgery and Postoperative Patient Outcomes. J Cardiothorac Vasc Anesth. Published 27 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →