Cardiothoracic & vascular anesthesia

Multimodal Pain Management Protocol with Anterior Chest Wall Fascial Plane Blocks Significantly Enhanced Recovery After Cardiac Surgery: A Single-Center Retrospective Cohort Study

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

The ERACS MPM with anterior chest wall blocks was associated with reductions in opioid use, ventilation hours, POAF, and LOS, suggesting improved perioperative outcomes.

Study context

Population
Adults undergoing elective cardiac surgery via median sternotomy, university hospital, January 1, 2021, to August 31, 2022
Participants
463 adults
Exposure
Pre-ERACS vs Post-ERACS
  • Pre-ERACSn = 247reference
  • Post-ERACSn = 216
Outcome
Intraoperative opioid dose and 48-hour postoperative opioid dose (MME)
Methodological detailssingle-centre, multivariable regression
  • Single-centre
  • Multivariable regression

Main finding

As reported in the abstract

Intraoperative opioid dose and 48-h postoperative opioid dose (MME)

Intraoperative opioid dose: statistically significant reduction

−0.63

multivariable regression ß; 95% CI −0.72 to −0.54p < 0.0001

Observational data: associations, not effects.

Secondary outcomes

Total postoperative ventilation hours

Statistically significant reduction
−0.59 (multivariable regression ß; 95% CI −1.16 to −0.02; p = 0.04)

Hospital length of stay (LOS)

Statistically significant reduction
−0.15 (multivariable regression ß; 95% CI, 0.22 to −0.08; p < 0.0001)

Postoperative AF (postoperative atrial fibrillation (POAF))

Statistically significant reduction
−0.46 (multivariable regression ß; 95% CI, −0.91 to −0.02; p = 0.04)

Original publication

Multimodal Pain Management Protocol with Anterior Chest Wall Fascial Plane Blocks Significantly Enhanced Recovery After Cardiac Surgery: A Single-Center Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 22 June 2025. doi:10.1053/j.jvca.2025.06.034

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