Respiratory failure & ventilation

Music Therapy During Weaning From Invasive Mechanical Ventilation in the ICU: A Randomized Controlled Trial

Crit Care MedPublished Randomized controlled trial with two parallel groups

Authors' conclusion

Music therapy may serve as a nonpharmacological complementary adjunct during weaning by reducing agitation, sedation, and tracheostomy rate. It may potentially decrease perceived stress and IMV and ICU stay durations. Further research is warranted.

Study context

Population
Adult critically ill patients admitted to a general ICU who received invasive mechanical ventilation (IMV) for at least 48 hours
Participants
100 adult critically ill patients
Comparison
MG vs Control group
Primary endpoint
Weaning duration

Primary result

As reported in the abstract

  • MG vs Control group: P = 0.97

Further findings

OutcomeP value
Percentage requiring propofolLower percentage in the MG groupP = 0.028
Perceived Stress Scale-14 scores · after 90 daysLower scores in the MGP = 0.24
Tracheostomy ratesMG significantly reduced tracheostomy rates (14%)P = 0.025
Median total IMV and ICU stay durationMG vs Control group · total IMV duration shorter in the MG group, not significantP = 0.206
Median total IMV and ICU stay durationMG vs Control group · ICU stay duration shorter in the MG group, not significantP = 0.203

Agitation and sedation levels (Richmond Agitation-Sedation Scale) · days 1 and 3

Significant improvements in the MG group (p = 0.048, 0.005, and 0.024)

Perceived pain (Visual Analog Pain Scale)

No significant difference

Heart rate, respiratory rate, blood pressure, and oxygenation before and after music therapy (MG)

No significant difference before and after music therapy

Original publication

Music Therapy During Weaning From Invasive Mechanical Ventilation in the ICU: A Randomized Controlled Trial. Crit Care Med. Published 21 October 2026. doi:10.1097/ccm.0000000000007372

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