Cardiac arrest & resuscitation

Neurological prognosis prediction upon arrival at the hospital after out-of-hospital cardiac arrest: R-EDByUS score

ResuscitationPublished Prognostic model development and internal validation study

An erratum to this article was published (Resuscitation, Dec 2025 ↗)

Authors' conclusion

The R-EDByUS score accurately predicted the neurological prognosis of cardiogenic OHCA upon hospital arrival.

Study context

Population
Adults with out-of-hospital cardiac arrest (OHCA) of presumed cardiac aetiology, All-Japan Utstein Registry, 2005–2019prehospital return of spontaneous circulation (ROSC) 67,064
Participants
942,891 adults
Comparison
Regression-based model vs Simplified model
Outcome
Unfavorable neurological outcome (Cerebral Performance Category 3, 4, or 5)
Follow-up
1 month
Methodological detailsregistry-based, bootstrap internal validation
  • Registry-based
  • Bootstrap internal validation

Performance

As reported in the abstract

Prediction of unfavorable neurological outcome (C-statistic)
Test or modelC-statistic, prehospital ROSC cohortBootstrap-validated C-statistic, prehospital ROSC cohortC-statistic, ongoing cardiopulmonary resuscitation (CPR) cohortBootstrap-validated C-statistic, ongoing CPR cohort
Regression-based model0.8510.8520.8720.852
Simplified model0.8420.8410.8650.841

C-statistic, prehospital ROSC cohort

Regression-based model0.851
Simplified model0.842

Bootstrap-validated C-statistic, prehospital ROSC cohort

Regression-based model0.852
Simplified model0.841

C-statistic, ongoing cardiopulmonary resuscitation (CPR) cohort

Regression-based model0.872
Simplified model0.865

Bootstrap-validated C-statistic, ongoing CPR cohort

Regression-based model0.852
Simplified model0.841

Further findings

Unfavorable neurological outcome, by cohort · 1 month

Prehospital ROSC cohort
46,971 (70.0%)
Ongoing CPR cohort
870,991 (99.4%)

Original publication

Neurological prognosis prediction upon arrival at the hospital after out-of-hospital cardiac arrest: R-EDByUS score. Resuscitation. Published 31 May 2024. doi:10.1016/j.resuscitation.2024.110257

Composed by AI from the published abstract and checked against it. How Briefs are made →

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