Cardiac arrest & resuscitation
Neurological prognosis prediction upon arrival at the hospital after out-of-hospital cardiac arrest: R-EDByUS score
An erratum to this article was published (Resuscitation, Dec 2025 ↗)
Authors' conclusion
The R-EDByUS score accurately predicted the neurological prognosis of cardiogenic OHCA upon hospital arrival.
Study context
- Population
- Adults with out-of-hospital cardiac arrest (OHCA) of presumed cardiac aetiology, All-Japan Utstein Registry, 2005–2019prehospital return of spontaneous circulation (ROSC) 67,064
- Participants
- 942,891 adults
- Comparison
- Regression-based model vs Simplified model
- Outcome
- Unfavorable neurological outcome (Cerebral Performance Category 3, 4, or 5)
- Follow-up
- 1 month
Methodological detailsregistry-based, bootstrap internal validation
- Registry-based
- Bootstrap internal validation
Performance
As reported in the abstract
Prediction of unfavorable neurological outcome (C-statistic)
| Test or model | C-statistic, prehospital ROSC cohort | Bootstrap-validated C-statistic, prehospital ROSC cohort | C-statistic, ongoing cardiopulmonary resuscitation (CPR) cohort | Bootstrap-validated C-statistic, ongoing CPR cohort |
|---|---|---|---|---|
| Regression-based model | 0.851 | 0.852 | 0.872 | 0.852 |
| Simplified model | 0.842 | 0.841 | 0.865 | 0.841 |
C-statistic, prehospital ROSC cohort
Regression-based model0.851
Simplified model0.842
Bootstrap-validated C-statistic, prehospital ROSC cohort
Regression-based model0.852
Simplified model0.841
C-statistic, ongoing cardiopulmonary resuscitation (CPR) cohort
Regression-based model0.872
Simplified model0.865
Bootstrap-validated C-statistic, ongoing CPR cohort
Regression-based model0.852
Simplified model0.841
Further findings
Unfavorable neurological outcome, by cohort · 1 month
- Prehospital ROSC cohort
- 46,971 (70.0%)
- Ongoing CPR cohort
- 870,991 (99.4%)
Original publication
Neurological prognosis prediction upon arrival at the hospital after out-of-hospital cardiac arrest: R-EDByUS score. Resuscitation. Published 31 May 2024. doi:10. 1016/ j. resuscitation. 2024. 110257
Composed by AI from the published abstract and checked against it. How Briefs are made →