Respiratory failure & ventilation
A non-invasive continuous and real-time volumetric monitoring in spontaneous breathing subjects based on bioimpedance—ExSpiron®Xi: a validation study in healthy volunteers
Authors' conclusion
Non-invasive TV, TV/IBW and RR estimation by ExSpiron®Xi was strongly correlated with tidal ventilation according to the gold standard spirometer technique. This data was not confirmed for MV. The calibration of the device did not improve its performance.
Study context
- Population
- Healthy volunteers breathing spontaneously5 men · 8 women
- Participants
- 13 volunteers
- Comparison
- ExSpiron®Xi vs spirometry, non-calibrated and calibrated
- Outcome
- Accuracy, precision and trending ability of ExSpiron®Xi TV measurements vs spirometry
Methodological detailsprospective, repeated measurements within each subject
- Prospective
- Repeated measurements within each subject
Performance
As reported in the abstract
Agreement and trending ability of TV, TV/IBW, RR and MV
Trending ability excellent for tidal volume (TV), TV/IBW and RR; concordance rate, calibrated and non-calibrated
>95%
Further findings
Determinants of absolute error (TV, TV/IBW, minute ventilation (MV))
- Absolute error variably associated with BMI, height and smoking status
- Accounting for repeated measurements
Original publication
A non-invasive continuous and real-time volumetric monitoring in spontaneous breathing subjects based on bioimpedance—ExSpiron®Xi: a validation study in healthy volunteers. J Clin Monit Comput. Published 19 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →