Perioperative medicine & outcomes
Noninvasive hemoglobin monitoring for maintaining hemoglobin concentration within the target range during major noncardiac surgery: A randomized controlled trial
Primary resultResult — go to the resultRelative risk 0.24 95% CI 0.13–0.41Authors' conclusion
Compared with routine care, SpHb-guided management resulted in significantly lower rates of hemoglobin deviation outside the target range intraoperatively in patients undergoing major noncardiac surgeries with a potential risk of hemorrhage.
Study context
- Population
- Patients undergoing elective major noncardiac surgery with a potential risk of hemorrhage, university hospital
- Participants
- 130 patients
- Comparison
- SpHb-guided management vs usual care
- Primary endpoint
- Rate of deviation of laboratory total hemoglobin from target range (8-14 g/dL): tests revealing deviation / total laboratory tests during surgery
- Follow-up
- Intraoperative
Methodological detailssingle-centre, prospective
- Single-centre
- Prospective
Primary result
As reported in the abstract
Relative risk
0.24
95% CI 0.13–0.41
P < 0.001
Events by treatment group
SpHb vs Control
RR 0.24 (95% CI 0.13–0.41); P < 0.001
Further findings
Patients receiving intraoperative RBC transfusion · no significant difference
P = 0.201
Unnecessary RBC preparation (>2 units)
P = 0.024
Median
| Outcome | SpHb | Control | P value |
|---|---|---|---|
| Number of point-of-care blood tests | 2 (IQR 1–4) | 4 (IQR 2–5) | P < 0.001 |
Original publication
Noninvasive hemoglobin monitoring for maintaining hemoglobin concentration within the target range during major noncardiac surgery: A randomized controlled trial. J Clin Anesth. Published 20 November 2023. doi:10. 1016/ j. jclinane. 2023. 111326
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