Haemodynamics, fluids & transfusion
Accuracy of minimally invasive hemoglobin monitoring in the perioperative period: transcutaneous hemoglobin monitoring and point-of-care testing devices: prospective observational study
Authors' conclusion
HemoCue® Hb801 provided accurate Hb measurement from a minimal arterial sample. SpHb (rev. O) had limited absolute accuracy and could not quantify the magnitude of change within accepted limits, but reliably indicated its direction. A hybrid approach-continuous SpHb monitoring triggering confirmatory HemoCue® measurement-may support safer perioperative hemoglobin management.
Study context
- Population
- Patients undergoing general anesthesia with invasive arterial monitoring for surgery with anticipated blood losspatients enrolled prospectively, 281 arterial blood samples analyzed
- Participants
- Fifty patients
- Exposure
- Continuous pulse hemoglobin (SpHb) (Revision O: rev. O) and intermittent point-of-care testing (POCT) using HemoCue® Hb801-against an automated hematology analyzer as the reference standard
- Outcome
- Agreement of HemoCue® Hb801 with the reference
Main finding
As reported in the abstract
R
0.979
Bias
0.119 g/dL
Limits of agreement [LOA]
−0.687 to +0.925 g/dL
Observational data: associations, not effects.
Further findings
Agreement of SpHb with the reference
- R
- 0.777
- LOA
- - 2.114 to +2.811 g/dL
- Greater random error at perfusion index <1.4
- 87/281 measurements, 31.0%
- Proportional bias
SpHb trend-tracking (polar plot analysis of 23 successive-change pairs from 9 patients)
- Angular bias
- - 5.8° (95% CI −12.2° to +0.5°)
- Four-quadrant concordance
- 100%
- Radial limits of agreement
- - 36.3° to +24.6°
- Exceeded the ±30° criterion
Original publication
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