Hemodynamics, fluids & transfusion

Norepinephrine pharmacolexicology: a chronological review of dose reporting and the implications of salt formulations

Intensive Care MedPublished Narrative review with systematic search

Authors' conclusion

National efforts-such as the United States Salt Policy and the French implementation model-offer a structured pathway toward harmonization.

Study context

Population
Studies addressing variability in norepinephrine salt formulations and labeling practices, evolution of pharmacological understanding, and proposed guidelines
Outcome
Norepinephrine salt formulations and dose reporting
Methodological detailssystematic search of PubMed/MEDLINE, EMBASE, and Google Scholar, narrative synthesis, chronological organisation
  • Systematic search of PubMed/MEDLINE, EMBASE, and Google Scholar
  • Narrative synthesis
  • Chronological organisation

Main finding

As reported in the abstract

  • National efforts (US Salt Policy, French implementation model) offer a structured pathway toward harmonization of norepinephrine dose reporting

Original publication

Norepinephrine pharmacolexicology: a chronological review of dose reporting and the implications of salt formulations. Intensive Care Med. Published 29 July 2025. doi:10.1007/s00134-025-08053-2

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