Optimal bispectral index exists in healthy patients undergoing general anesthesia: A validation study
Authors' conclusion
We demonstrate the presence of BISopt in the general anesthesia population (96% of patients), and its absence in awake controls, providing preliminary validation of its existence outside of neural injury populations.
Study context
- Population
- Healthy patients undergoing elective spinal surgery under GA and healthy awake volunteers
- Comparison
- General anesthesia vs awake controls
- Outcome
- Presence of BISopt (relationship between BIS and continuous cerebrovascular reactivity)
Methodological detailsexploratory
- Exploratory
Performance
As reported in the abstract
Presence of BISopt
General anesthesia
96%
Further findings
- BIS sufficiently separate from overall systemic BP
Original publication
Optimal bispectral index exists in healthy patients undergoing general anesthesia: A validation study. J Clin Monit Comput. Published 4 March 2024. doi:10.
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