Outcomes After Respiratory Extracorporeal Life Support in Teens and Young Adults: An Extracorporeal Life Support Organization Registry Analysis*
Main finding · Survival to dischargeResult — go to the resultAdjusted OR for survival 1.14 95% CI 1.004–1.3Authors' conclusion
In this large multicenter retrospective study, mortality was higher in teens than in young adults who received respiratory ECLS.
Study context
- Population
- Patients aged 16–30 years cannulated for respiratory indications, Extracorporeal Life Support Organization registry, 1990 to 2020
- Participants
- 5,751 patients
- Exposure
- Teens vs young adults receiving respiratory extracorporeal life support (ECLS)
- Teensn = 1,653reference
- Young adultsn = 4,098
- Outcome
- Survival to discharge
Methodological detailsmulticentre registry
- Multicentre registry
Main finding
As reported in the abstract
Adjusted OR for survival
1.14
95% CI 1.004–1.3
By group
Young adults vs Teens
adjusted OR for survival 1.14 (95% CI 1.004–1.3)
Observational data: associations, not effects.
Further findings
Use of venoarterial ECLS
Survival by PaO2/FiO2 stratum (subgroup)
- Severity of illness higher in teens; survival within each PaO2/FiO2 stratum higher in young adults than teens
High-frequency oscillatory ventilation
- Teens more likely to receive HFOV; associated with longer time from admission to ECLS initiation
Original publication
Outcomes After Respiratory Extracorporeal Life Support in Teens and Young Adults: An Extracorporeal Life Support Organization Registry Analysis*. Crit Care Med. Published 5 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →