Outcomes in Adult Patients Requiring Multiple Runs of Extracorporeal Membrane Oxygenation
Authors' conclusion
Acute renal failure, postcardiotomy cardiogenic shock, age >40 years, and preexisting right ventricular systolic dysfunction predict poor survival rates.
Study context
- Population
- Adults (≥18 years) supported with multiple runs of extracorporeal membrane oxygenation (ECMO) (venoarterial or venovenous) during the same hospitalization, single quaternary care academic centerof 451 reviewed
- Participants
- 46 adults
- Outcome
- Survival
Methodological detailsretrospective chart review, single-centre
- Retrospective chart review
- Single-centre
Main finding
As reported in the abstract
Survived to 90 days and hospital discharge
10
21.7%
Survived to ≥1 year
9
19.5%
Observational data: associations, not effects.
Further findings
Factors associated with poor outcomes
- Acute renal failure during first ECMO run, postcardiotomy cardiogenic shock as indication for first cannulation, right ventricular systolic dysfunction prior to first cannulation, and age ≥40 years associated with poor outcomes
Number of ECMO runs and indications
- Two runs
- 44
- Three runs
- 2
- Initial indication postcardiotomy cardiogenic shock
- 72%
- Initial indication cardiogenic shock
- 24%
- Initial indication refractory hypoxia
- 2%
- Venoarterial ECMO during first run
- 43 (93%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Outcomes in Adult Patients Requiring Multiple Runs of Extracorporeal Membrane Oxygenation. J Cardiothorac Vasc Anesth. Published 5 August 2025. doi:10.
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