Venoarterial Extracorporeal MembraneOxygenation in Septic Shock and/or Sepsis-induced Cardiomyopathy: A Systematic Review of Fifteen Studies
Authors' conclusion
Venoarterial extracorporeal membrane oxygenation may provide meaningful survival benefits in carefully selected patients with severe, refractory septic shock and/or sepsis-induced cardiomyopathy.
Study context
- Population
- Adults with septic shock and/or sepsis-induced cardiomyopathy undergoing VA-ECMO, ICUs at multiple international centres
- Participants
- 1,110 adults · 15 studies
- Outcome
- Survival to hospital discharge
Pooled result
As reported in the abstract
Survival to hospital discharge (pooled)
Pooled survival rate
42%
Further pooled results
Patient profile at VA-ECMO initiation
- Age, mean ± SD (years)
- 52 ± 6
- MAP (mmHg)
- 62 ± 8
- pH
- 7.20 ± 0.07
- Lactate (mmol/L)
- 9 ± 6
- PaO₂/FiO₂
- 85 ± 20
- Ejection fraction
- 33% ± 15
- Inotrope score (μg/kg/min)
- 122 ± 99
- SOFA score
- 15 ± 3
- Severe hemodynamic instability
Original publication
Venoarterial Extracorporeal MembraneOxygenation in Septic Shock and/or Sepsis-induced Cardiomyopathy: A Systematic Review of Fifteen Studies. J Cardiothorac Vasc Anesth. Published 2 October 2025. doi:10.
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