Outcomes of Extremely Prolonged (> 50 d) Venovenous Extracorporeal Membrane Oxygenation Support
Authors' conclusion
Our experience suggests that extremely prolonged venovenous ECMO support to allow native lung recovery or optimization for lung transplantation may be a feasible strategy in select critically ill patients
Study context
- Population
- Adults ≥18 y with acute respiratory failure receiving venovenous extracorporeal membrane oxygenation (ECMO) > 50 days, cannulated January 2018–January 2022, large tertiary urban care centerof 130 on VV ECMO
- Participants
- 12 adults
- Outcome
- Outcomes of extremely prolonged VV ECMO
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Duration of VV ECMO support, median (IQR 70-128 d; maximum 180 days)
- 94 days
- Successful weaning of VV ECMO
- 8 (67%)
- Bridged to lung transplantation
- 6 (50%)
- Bridged to recovery
- 2 (17%)
- Discharged from hospital, of those weaned
- 7 (88%)
- Alive 6 months post-decannulation, of those discharged
- 7
- Alive 1 year after decannulation, of those with sufficient follow-up
- 83% (5/6)
Observational data: associations, not effects.
Further findings
Patient characteristics and course
- Adult respiratory distress syndrome (ARDS) secondary to COVID-19
- 11 (92%)
- Age, median (IQR 35-51 yr)
- 39 years
- Time from intubation to cannulation, median (IQR 2-14 d)
- 5 days
- Mobilized while on VV ECMO
- 9 (75%)
Original publication
Outcomes of Extremely Prolonged (> 50 d) Venovenous Extracorporeal Membrane Oxygenation Support. Crit Care Med. Published 16 March 2023. doi:10.
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