Peri-operative dexmedetomidine and emergence agitation in adults undergoing nasal surgery: A systematic review and meta-analysis
Pooled result · Emergence agitationResult — go to the resultRelative risk 0.31 95% CI 0.19–0.49Authors' conclusion
The use of dexmedetomidine significantly reduces the incidence of emergence agitation in patients undergoing nasal surgeries under general anaesthesia.
Study context
- Population
- Adults undergoing nasal surgery under GA
- Participants
- 620 adults · 9 RCTs
- Comparison
- Peri-operative dexmedetomidine vs placebo
- Outcome
- Incidence of emergence agitation during anaesthetic recovery
Methodological detailstrial sequential analysis, leave-one-out sensitivity analysis
- Trial sequential analysis
- Leave-one-out sensitivity analysis
Pooled result
Emergence agitation
Relative risk
0.31
95% CI 0.19–0.49
P < 0.0001
Dexmedetomidine vs Placebo
RR 0.31 (95% CI 0.19–0.49); P < 0.0001
As reported in the abstract
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Peri-operative dexmedetomidine and emergence agitation in adults undergoing nasal surgery: A systematic review and meta-analysis. Eur J Anaesthesiol. Published 6 March 2025. doi:10.
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