Pericapsular nerve group block with phenol for non‐operative hip fracture management in patients living with frailty: a prospective multicentre cohort study
Authors' conclusion
The pericapsular nerve group block with phenol 6% is an effective, minimally invasive procedure for pain management in addition to opioid-based pain relief in patients living with frailty, when surgery is not chosen.
Study context
- Population
- Patients living with frailty choosing non-operative management for a hip fracture and meeting the indication for neurolysis, seven Dutch hospitals
- Participants
- 103 patients
- Outcome
- Patient-reported pain
- Follow-up
- 1 week
Methodological detailsmulticentre, Second needle placement in 14/103 (14%), Mean (SD) injected volume of phenol 6% 10 (3.1) ml, Mean (SD) age 87 (6.4) y; 51% nursing home residents; 76% cognitive impairment
- Multicentre
- Second needle placement in 14/103 (14%)
- Mean (SD) injected volume of phenol 6% 10 (3.1) ml
- Mean (SD) age 87 (6.4) y; 51% nursing home residents; 76% cognitive impairment
Main finding
As reported in the abstract
Acceptable pain at rest
34 of 36
94%
No or acceptable pain when washing and dressing
47 of 53
89%
Observational data: associations, not effects.
Further findings
Bed-chair transfer possible · 1 week
- Bed-chair transfer possible
- 24/53 (45%)
Mortality and survival
- Mortality after 3 months
- 72/91 (79%)
- 30-day mortality
- 56/91 (62%)
- Median (IQR [range]) survival, days
- 9 (6-24 [0-85])
Safety
- No procedure-related adverse events reported
Original publication
Pericapsular nerve group block with phenol for non‐operative hip fracture management in patients living with frailty: a prospective multicentre cohort study. Anaesthesia. Published 8 September 2026. doi:10.
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