Cardiothoracic & vascular anesthesia
Perioperative EEG background and discharge abnormalities in children undergoing cardiac surgery: a prospective single-centre observational study
Authors' conclusion
Perioperative EEG abnormalities occurred frequently and correlated with numerous demographic and perioperative variables and adversely correlated with postoperative EEG abnormalities and early outcomes.
Study context
- Population
- Children with heterogeneous congenital heart disease undergoing cardiac surgery
- Participants
- 437 children
- Outcome
- Perioperative EEG abnormalities
Methodological detailssingle-centre, Postoperative brain MRI before discharge, EEG monitored preoperatively in 139, intraoperatively in 215 and postoperatively in 437 patients
- Single-centre
- Postoperative brain MRI before discharge
- EEG monitored preoperatively in 139, intraoperatively in 215 and postoperatively in 437 patients
Main finding
As reported in the abstract
- Intraoperative progression to isoelectric EEG
- 106/215 (49.3%)
- Postoperative background abnormalities
- 218/437 (49.9%)
- Postoperative background abnormalities not recovered after surgery
- 119 (54.6%)
- Seizures
- 36/437 (8.2%)
- Spikes/sharp waves
- 359/437 (82.2%)
- Pathological delta brushes
- 9/437 (2.0%)
Observational data: associations, not effects.
Further findings
Preoperative background abnormalities and later EEG abnormalities
- Patients with preoperative background abnormalities (n=40) had more severe intraoperative and postoperative EEG abnormalities
- P < 0.0001
Duration of isoelectric EEG
- Longer isoelectric EEG associated with more severe postoperative EEG abnormalities and brain injury on MRI
- Ps≤0.003
Postoperative EEG abnormalities and brain injury on MRI
- Postoperative EEG abnormalities correlated with degree of brain injury on MRI
- Ps≤0.02
Postoperative EEG abnormalities and clinical outcomes
- Demographic and perioperative variables significantly correlated with postoperative EEG abnormalities, which correlated with adverse clinical outcomes
Original publication
Perioperative EEG background and discharge abnormalities in children undergoing cardiac surgery: a prospective single-centre observational study. Br J Anaesth. Published 14 June 2023. doi:10.
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