Pediatric anesthesia & critical care
Perioperative intravenous lignocaine for pediatric postoperative pain—A systematic review and meta‐analysis
Pooled result · Morphine consumption, first 24 h after surgeryResult — go to the resultSMD −1.31 95% CI −2.18 to −0.43Authors' conclusion
There is low quality evidence to suggest that perioperative intravenous lignocaine bolus followed by an infusion significantly reduced the opioid consumption on the first postoperative day in pediatric surgical patients. The effects of perioperative lignocaine on postoperative pain scores and the need for rescue analgesia are uncertain.
Study context
- Population
- Pediatric patients (≤18 years) undergoing surgery under GA
- Participants
- 415 patients · 7 studies
- Comparison
- Perioperative IV lignocaine vs placebo
- Outcome
- Postoperative opioid consumption
- Follow-up
- 24 h
Pooled result
Morphine consumption, first 24 h after surgery
SMD
−1.31
95% CI −2.18 to −0.43
P = 0.003
Lignocaine vs Placebo
SMD −1.31 (95% CI −2.18 to −0.43); P = 0.003
As reported in the abstract
Further pooled results
Postoperative pain scores and need for rescue analgesia
- Meta-analysis could not be performed
Original publication
Perioperative intravenous lignocaine for pediatric postoperative pain—A systematic review and meta‐analysis. Paediatr Anaesth. Published 4 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →