Pediatric anesthesia & critical care
Perioperative Management of Pediatric Combined Heart and Liver Transplantation: A 17 year single center experience
Authors' conclusion
Perioperative challenges include major perioperative bleeding, unstable hemodynamics, and end organ injury including acute kidney injury and neurological events.
Study context
- Population
- Pediatric patients undergoing combined heart and liver transplantation at Stanford Children's Hospital, 2006 to 202215 (83%) failing Fontan
- Participants
- 18 patients
- Outcome
- Perioperative management, identifying challenges and potential solutions
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Surgical procedure time, median [IQR] (h)
- 13.4 [11.5, 14.5]
- CPB time, median (h)
- 4.3 [3.9, 5.8]
- Total blood products transfused in OR post CPB, median (mLs/kg)
- 89.4 [63.9, 127.0]
- Vasoplegia during CPB
- 9 (50%)
- Activated PCC used post CPB
- 15 (83%)
- Time to extubation, median (days)
- 4.0 [2.8, 6.5]
- ICU LOS, median (days)
- 20.0 [7.8, 48.3]
- Hospital LOS, median (days)
- 54.0 [30.5, 68.3]
- 30-day and 1-year survival
- 89%
Observational data: associations, not effects.
Safety
30-day thromboembolism
- 30-day thromboembolism rate
- 22%
RRT
- Incidence of RRT
- 11%
- RRT required at hospital discharge
- 0
Neurological events · 30 days
- Neurological events within 30 days
- 17%
Original publication
Perioperative Management of Pediatric Combined Heart and Liver Transplantation: A 17 year single center experience. Paediatr Anaesth. Published 8 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →