Cardiothoracic & vascular anesthesia
Perioperative Risk Factors of Acute Kidney Injury After Heart Transplantation and One-Year Clinical Outcomes: A Retrospective Cohort Study
Authors' conclusion
This study highlighted the high incidence of acute kidney injury after heart transplantation and its impact on patient outcomes.
Study context
- Population
- All patients who underwent heart transplantation, January 2015 to December 2020, university hospital
- Participants
- 209 patients
- Exposure
- AKI vs no AKI after heart transplantation
- AKIn = 134
- Outcome
- Incidence of posttransplantation AKI
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
AKI
64%
134
- High BMI independently associated with AKI
- OR per kg/m² 1.18 (95% CI 1.02-1.38, p = 0.030)
- Prolonged cold ischemic period independently associated with AKI
- OR per 10 minutes 1.11 (95% CI 1.01-1.24, p = 0.039)
- High dose of intraoperative dobutamine independently associated with AKI
- OR per µg/kg/min 1.24 (95% CI 1.06-1.46, p = 0.008)
Observational data: associations, not effects.
Further findings
Mortality · 1 year
P = 0.015
Worsened renal function vs pre-transplantation, among 1-year survivors
- Survivors with worsened renal function (of 172 survivors)
- 82 (48%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Perioperative Risk Factors of Acute Kidney Injury After Heart Transplantation and One-Year Clinical Outcomes: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 22 March 2024. doi:10.
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