Cardiothoracic & vascular anesthesia
The Impact of Acute Kidney Injury on Chronic Kidney Disease After Cardiac Surgery: A Systematic Review and Meta-analysis
Authors' conclusion
Acute kidney injury after cardiac surgery was associated with a more than 5-fold increased odds of developing CKD. New-onset CKD occurred in almost 1 in 4 patients in the years after surgery.
Study context
- Population
- Adult cardiac surgery patients without preoperative kidney impairment or prior transplant; kidney follow-up ≥90 days12 studies
- Comparison
- Postoperative AKI vs no AKI after cardiac surgery
- Outcome
- Incident CKD (AKI vs no AKI after cardiac surgery)
Methodological detailsMedline and Embase searched from 1974 to February 6, 2023
- Medline and Embase searched from 1974 to February 6, 2023
Pooled result
As reported in the abstract
- AKI associated with increased odds of chronic kidney disease (CKD) in all individual studies
Further pooled results
AKI occurrence across studies
- Mean AKI occurrence (minimum-maximum: 8-50)
- 16%
Incident CKD occurrence across studies
- Mean CKD occurrence (minimum-maximum: 3-35)
- 24%
- High variability depending on definitions and follow-up time
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The Impact of Acute Kidney Injury on Chronic Kidney Disease After Cardiac Surgery: A Systematic Review and Meta-analysis. J Cardiothorac Vasc Anesth. Published 2 April 2024. doi:10.
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