Cardiothoracic & vascular anesthesia
Days Alive and Out of the Hospital After Heart Transplantation: A Retrospective Cohort Study
Authors' conclusion
In this analysis of patients undergoing orthotopic heart transplantation, there was no significant difference in DAOH365 in patients with prior MCS as a bridge to transplant compared to those without MCS.
Study context
- Population
- Adults undergoing orthotopic heart transplantation, January 1, 2015 to January 1, 2020
- Participants
- 235 adults
- Exposure
- Mechanical circulatory support (MCS) as bridge to transplant vs no prior MCS
- MCSn = 103
- Without MCSn = 132reference
- Outcome
- Days alive and out of the hospital (DAOH) at 365 days (DAOH365) after orthotopic heart transplant
- Follow-up
- 365 days
Methodological detailssingle-centre, academic tertiary referral center
- Single-centre
- Academic tertiary referral center
Main finding
As reported in the abstract
DAOH365
P = 0.43
Observational data: associations, not effects.
Further findings
DAOH365, entire cohort · 365 days
- Median DAOH365 entire cohort, days (IQR 335.0-354.0)
- 348
Predictors of reduced DAOH365 (multivariate Poisson regression)
- Transplant after the 2018 heart transplant allocation change, pretransplant pulmonary hypertension and increased total ischemic time predicted reduced DAOH365
Original publication
Days Alive and Out of the Hospital After Heart Transplantation: A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 30 September 2023. doi:10.
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