Cardiothoracic & vascular anesthesia
Peripheral Regional Anesthetic Techniques in Cardiac Surgery: A Systematic Review and Meta-Analysis
Authors' conclusion
Compared to no RA or placebo, PRA may reduce pain intensity at rest and during movement.
Study context
- Population
- Adults and children undergoing cardiac surgery
- Participants
- 2,044 adults · 33 randomized controlled trials (RCTs)
- Comparison
- Peripheral regional anesthesia (RA) vs no RA, placebo or neuraxial anaesthesia
- Outcome
- Pain intensity
- Follow-up
- 24 hours after surgery
Methodological detailsCochrane RoB 1 risk of bias assessment, GRADE certainty of evidence, 24 of 33 RCTs had a high risk of bias; 28 were performed in adults
- Cochrane RoB 1 risk of bias assessment
- GRADE certainty of evidence
- 24 of 33 RCTs had a high risk of bias; 28 were performed in adults
Pooled result
As reported in the abstract
MD, points (95% CI)
PRA vs No RAat rest; I2 = 92%; very low certainty evidence
−0.81(−1.51 to −0.10)
PRA vs Placeboat rest; I2 = 54%; very low certainty evidence
−1.36(−1.59 to −1.13)
PRA vs Placeboduring movement; I² = 72%; very low certainty evidence
−1.00(−1.34 to −0.67)
Further pooled results
Pediatric cardiac surgery
- No data could be meta-analyzed due to the low number of included trials
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Peripheral Regional Anesthetic Techniques in Cardiac Surgery: A Systematic Review and Meta-Analysis. J Cardiothorac Vasc Anesth. Published 26 October 2023. doi:10.
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