Perioperative medicine & outcomes

Personalized perioperative blood pressure management in patients having major non-cardiac surgery: A bicentric pilot randomized trial

J Clin AnesthPublished Randomised controlled trial

Authors' conclusion

It seems feasible to determine the effect of personalized perioperative blood pressure management maintaining intraoperative MAP above the preoperative mean nighttime MAP on postoperative complications in a large multicenter trial.

Study context

Population
Patients ≥ 45 years old having major non-cardiac surgery105 enrolled
Participants
98 patients
Comparison
Personalized BP management vs intraoperative mean arterial pressure (MAP) above 65 mmHg
Methodological detailspilot, bicentric, University Medical Center Hamburg-Eppendorf and RWTH Aachen University Hospital, Germany
  • Pilot
  • Bicentric
  • University Medical Center Hamburg-Eppendorf and RWTH Aachen University Hospital, Germany

Primary result

As reported in the abstract

Personalized blood pressure management

3.29

median · IQR 1.64–6.82 · mmHg

Patients

Preoperative automated nighttime BP monitoring possible
98 (93 %)
Preoperative mean nighttime MAP clinically meaningfully differed from 65 mmHg
83 (85 %)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Personalized perioperative blood pressure management in patients having major non-cardiac surgery: A bicentric pilot randomized trial. J Clin Anesth. Published 27 November 2024. doi:10.1016/j.jclinane.2024.111687

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