Cardiothoracic & vascular anaesthesia

Phase-dependent agreement between noninvasive and invasive blood pressure monitoring during transcatheter aortic valve replacement: a prospective observational study

Can J AnaesthPublished Prospective observational study

Authors' conclusion

ClearSight showed phase-dependent agreement with IAP during TAVR, typically underestimating systolic and mean pressures, with improved agreement during hemodynamic stability, most notably after protamine.

Study context

Population
Patients undergoing transcatheter aortic valve replacement (TAVR) at a tertiary academic hospital987 paired measurements
Participants
21 patients
Exposure
ClearSight noninvasive BP vs invasive arterial pressure
Outcome
Phase-dependent agreement between ClearSight and IAP across intraoperative phases of TAVR
Methodological detailssingle-centre, method-comparison (Bland-Altman with linear mixed-effects modeling)
  • Single-centre
  • Method-comparison (Bland-Altman with linear mixed-effects modeling)

Main finding

As reported in the abstract

Mean bias (IAP minus ClearSight), after outlier exclusion

Mean bias, systolic

+14 mm Hg

Mean bias, mean

+6 mm Hg

Mean bias, diastolic

−3 mm Hg

Observational data: associations, not effects.

Further findings

Intraclass correlation coefficients, before to after outlier removal

Systolic
0.69 to 0.72
Mean
0.65 to 0.68
Diastolic
0.59 to 0.63
Limits of agreement narrowed after outlier removal

Original publication

Phase-dependent agreement between noninvasive and invasive blood pressure monitoring during transcatheter aortic valve replacement: a prospective observational study. Can J Anaesth. Published 2 September 2026. doi:10.1007/s12630-026-03176-6

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