Respiratory failure & ventilation
Physiologic Effects of Reconnection to the Ventilator for 1 Hour Following a Successful Spontaneous Breathing Trial
Authors' conclusion
Significant alveolar derecruitment was observed at the end of an SBT and was markedly more pronounced with a T-piece than with PSV. Reconnection to the ventilator for 1 h allowed complete recovery of alveolar derecruitment.
Study context
- Population
- Patients after a successful spontaneous breathing trial (SBT)analysed
- Participants
- 25 patients
- Comparison
- T-piece vs pressure-support ventilation (PSV)
- T-piecen = 11
- PSVn = 14reference
- Primary endpoint
- Alveolar recruitment assessed by end-expiratory lung volume (EELV)
Methodological detailsphysiologic study
- Physiologic study
Primary result
As reported in the abstract
Change in EELV at end of SBT vs baseline · End of SBT
T-piece
−43%
95% CI −51–-35
PSV
−20%
95% CI −26–-13
P < 0.001
- End-expiratory lung volume (EELV) decrease overall vs baseline
- −30% (95% CI, −37 to −23)
Further findings
EELV after 1 h reconnection to the ventilator (% of baseline)
- EELV as % of baseline; not significantly different from pre-SBT (P = .104)
- 96% (95% CI, 92 to 101)
EELV recovery after 10 min reconnection
- PSV: completely recovered vs pre-SBT
- P = 0.574
- T-piece: remained lower than pre-SBT
- P = 0.010
Original publication
Physiologic Effects of Reconnection to the Ventilator for 1 Hour Following a Successful Spontaneous Breathing Trial. Chest. Published 29 January 2024. doi:10.
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