Plasma sodium during the recovery of renal function in critically ill adult patients: Multicenter prospective cohort study
Main finding · Association of daily fluid balance with daily plasma sodiumResult — go to the resultβ −0.26 95% CI −0.63-0.13Authors' conclusion
The increase in plasma sodium is common during AKI recovery and can only partially be attributed to the water and electrolyte balances.
Study context
- Population
- Critically ill adults with acute kidney injury (AKI) in 4 ICUs, followed during AKI recovery
- Participants
- 93 adults
- Outcome
- Daily plasma sodium (main exposure: daily fluid balance)
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Association of daily fluid balance with daily plasma sodium
β
−0.26
95% CI −0.63-0.13
P = 0.19
Observational data: associations, not effects.
Further findings
Predictors of total sodium variation
| β (95% CI) | P value | |
|---|---|---|
| Initial plasma sodiumLower initial sodium, higher variation | −0.40 (−0.53 to −0.27) | P < 0.01 |
| Initial urea | 0.07 (0.04–0.01) | P < 0.01 |
| Net sodium balance | 0.002 (0.0001–0.01) | P = 0.05 |
Plasma sodium increase and hypernatremia
- Plasma sodium increased
- 79 (85%)
- Hypernatremia
- 52%
Original publication
Plasma sodium during the recovery of renal function in critically ill adult patients: Multicenter prospective cohort study. J Crit Care. Published 24 February 2024. doi:10.
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