Platelet transfusions in adult thrombocytopenic ICU patients: Protocol for a sub‐study of the PLOT‐ICU cohort

Anthon, CT; Pène, F; Perner, A; Azoulay, E; Puxty, K; Van De Louw, A; Chawla, S; Castro, P; Povoa, P; Coelho, L; Metaxa, V; Kochanek, M; Liebregts, T; Kander, T; Sivula, M; Møller, MH; Russell, L

doi:10.1111/aas.14365

Platelet transfusions in adult thrombocytopenic intensive care unit (ICU) patients: Protocol for a sub‐study of the PLOT‐ICU cohort

Acta Anaesthesiol ScandPublished 19 Dec 2023Protocol and statistical analysis plan for a post hoc sub-study of the PLOT-ICU international inception cohort study

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Study context

Population: Adult thrombocytopenic ICU patients
Participants: 504 thrombocytopenic patients

Planned comparison: Apheresis-derived vs pooled whole-blood-derived platelet transfusions
Primary endpoint: Number of patients receiving platelet transfusion in the ICU by product type (apheresis-derived vs pooled whole-blood-derived)

Methodological detailsdescriptive, Follow-up 90 days, Baseline characteristics and secondary clinical outcomes stratified by platelet transfusion status in the ICU and severity of thrombocytopenia; data presented descriptively

Descriptive
Follow-up 90 days
Baseline characteristics and secondary clinical outcomes stratified by platelet transfusion status in the ICU and severity of thrombocytopenia; data presented descriptively

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Platelet transfusions in adult thrombocytopenic ICU patients: Protocol for a sub‐study of the PLOT‐ICU cohort. Acta Anaesthesiol Scand. Published 19 December 2023. doi:10.1111/aas.14365

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