Post-discharge functional outcomes in older patients with sepsis
Authors' conclusion
Elevated care needs and mortality were observed in patients with sepsis within 1 year post-discharge. Older patients with sepsis and higher baseline levels of care needs had a high association of all-cause mortality 1 year post-discharge.
Study context
- Population
- Patients with sepsis in 12 Japanese municipalities, Longevity Improvement & Fair Evidence study, April 2014–March 2022analysed at baseline
- Participants
- 17,648 patients
- Exposure
- Pre-sepsis care needs levels vs no care needs
- No care needsn = 7,982reference
- Support level and care needs level 1n = 3,736
- Care needs levels 2-3n = 3,089
- Care needs levels 4-5n = 2,841
- Outcome
- Changes in care needs level and all-cause mortality
- Follow-up
- 1 year post-discharge
Methodological detailsCox proportional hazard models, multicentre (12 municipalities)
- Cox proportional hazard models
- Multicentre (12 municipalities)
Main finding
As reported in the abstract
All-cause mortality
Each group vs no care needsHazard ratio (95% CI)
Support level and care needs level 1
1.05(0.96–1.15)
Care needs levels 2-3
1.46(1.33–1.60)
Care needs levels 4-5
1.92(1.75–2.10)
Observational data: associations, not effects.
Further findings
Distribution of care needs at 1 year post-discharge
- No care needs
- 4791 (27.1%)
- Support level and care needs level 1
- 2390 (13.5%)
- Care needs levels 2-3
- 2629 (14.9%)
- Care needs levels 4-5
- 3373 (19.1%)
- Death
- 4465 (25.3%)
Original publication
Post-discharge functional outcomes in older patients with sepsis. Crit Care. Published 29 August 2024. doi:10.
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