Cardiothoracic & vascular anaesthesia
Postoperative delirium: An independent risk factor for poorer quality of life with long-term cognitive and functional decline after cardiac surgery
Authors' conclusion
Postoperative delirium is a risk factor for decreased quality of life in patients 3 years after heart surgery, being associated with greater cognitive and functional deterioration, as well as greater risk of hospital readmission.
Study context
- Population
- Consecutive adults (≥18 years) undergoing cardiac surgery (DELIPRECAS study)
- Participants
- 313 adults
- Exposure
- Postoperative delirium vs no delirium
- Outcome
- Cognitive and functional status (telephone interview) and influence of CAM-ICU-diagnosed postoperative delirium
- Follow-up
- 3 years after cardiac surgery
Main finding
As reported in the abstract
Long-term cognitive and functional problems (delirium as independent risk factor) · 3 years
Delirium vs No deliriumOdds ratio (95% CI)P value
Memory problems
6.11(2.54–14.68)
P < 0.001Concentration
11.20(3.58–35.09)
P > 0.001Confusion/disorientation
10.93(3.61–33.12)
P > 0.001Nightmares
8.99(1.98–40.90)
P = 0.004Emotional problems
4.30(1.87–9.91)
P = 0.001Poorer mobility after hospital discharge
2.436(1.06–5.61)
P = 0.037- Sleep problems
- OR 5.21 (95% CI 2 0.29 to 11.84); P < 0.001
Observational data: associations, not effects.
Further findings
Hospital readmissions
P = 0.022
Original publication
Postoperative delirium: An independent risk factor for poorer quality of life with long-term cognitive and functional decline after cardiac surgery. J Clin Anesth. Published 1 December 2022. doi:10. 1016/ j. jclinane. 2022. 111030
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