Perioperative medicine & outcomes
Postoperative nausea and vomiting at Landspitali: A prospective study
Authors' conclusion
The incidence of PONV is generally low in this diverse surgical population where anaesthesia is mostly maintained with total intravenous anaesthesia and PONV prophylaxis is common.
Study context
- Population
- Adults ≥18 years admitted to the postoperative care unit (PACU) after elective or emergency operations, Landspitali University Hospital, Iceland, May-July 2022
- Participants
- 438 adults
- Outcome
- Incidence of PONV (self-reported moderate/severe nausea, 5/10 or higher on NRS)
Methodological detailsconvenience sample, single-centre, Questionnaires in the PACU and 24 h after discharge from PACU
- Convenience sample
- Single-centre
- Questionnaires in the PACU and 24 h after discharge from PACU
Main finding
As reported in the abstract
Moderate/severe nausea (≥5/10 on NRS), self-reported
Incidence in PACU
4%
Incidence on POD 1
3%
Worst nausea rated moderate/severe in PACU
7%
Worst nausea rated moderate/severe on POD 1
17%
Observational data: associations, not effects.
Further findings
Risk factors associated with postoperative nausea and vomiting (PONV)
| OR (95% CI) | ||
|---|---|---|
| Female gender | 1.90 (1.04–3.53) | |
| History of motion sickness or PONV | 2.74 (1.51–4.94) | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | OR (95% CI) | |
|---|---|---|
| Risk factors associated with PONVIncreasing age (per decade) · protective | 0.83 (0.71–0.98) | |
| 0.512Odds ratio (log scale) |
Anaesthesia practice
- Anaesthetics with intravenous medications only
- 91%
- Received ≥1 prophylactic medication for PONV
- 82%
Risk factors associated with PONV
- More Apfel risk factors associated with higher PONV incidence despite more liberal antiemetic use
Original publication
Postoperative nausea and vomiting at Landspitali: A prospective study. Acta Anaesthesiol Scand. Published 23 January 2024. doi:10. 1111/ aas. 14375
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