Perioperative medicine & outcomes

Postoperative nausea and vomiting at Landspitali: A prospective study

Acta Anaesthesiol ScandPublished Prospective cohort study

Authors' conclusion

The incidence of PONV is generally low in this diverse surgical population where anaesthesia is mostly maintained with total intravenous anaesthesia and PONV prophylaxis is common.

Study context

Population
Adults ≥18 years admitted to the postoperative care unit (PACU) after elective or emergency operations, Landspitali University Hospital, Iceland, May-July 2022
Participants
438 adults
Outcome
Incidence of PONV (self-reported moderate/severe nausea, 5/10 or higher on NRS)
Methodological detailsconvenience sample, single-centre, Questionnaires in the PACU and 24 h after discharge from PACU
  • Convenience sample
  • Single-centre
  • Questionnaires in the PACU and 24 h after discharge from PACU

Main finding

As reported in the abstract

Moderate/severe nausea (≥5/10 on NRS), self-reported

Incidence in PACU

4%

Incidence on POD 1

3%

Worst nausea rated moderate/severe in PACU

7%

Worst nausea rated moderate/severe on POD 1

17%

Observational data: associations, not effects.

Further findings

Risk factors associated with postoperative nausea and vomiting (PONV)

OR (95% CI)
Female gender1.90 (1.04–3.53)
History of motion sickness or PONV2.74 (1.51–4.94)
OutcomeOR (95% CI)
Risk factors associated with PONVIncreasing age (per decade) · protective0.83 (0.71–0.98)

Anaesthesia practice

Anaesthetics with intravenous medications only
91%
Received ≥1 prophylactic medication for PONV
82%

Risk factors associated with PONV

More Apfel risk factors associated with higher PONV incidence despite more liberal antiemetic use

Original publication

Postoperative nausea and vomiting at Landspitali: A prospective study. Acta Anaesthesiol Scand. Published 23 January 2024. doi:10.1111/aas.14375

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