Cardiothoracic & vascular anaesthesia
Pre‒Cardiopulmonary Bypass Furosemide Administration and Intraoperative Urinary Oxygen Tension During Coronary Artery Bypass Surgery: A Prospective Observational Study
Authors' conclusion
Pre-CPB furosemide administration was associated with a greater intraoperative reduction in PuO₂ during elective on-pump CABG, without significant differences in early postoperative renal outcomes.
Study context
- Population
- Adults undergoing elective isolated on-pump coronary artery bypass grafting (CABG) with preserved baseline renal function, tertiary cardiac surgery center
- Participants
- 122 adults
- Exposure
- Pre-CPB furosemide vs no furosemide
- Furosemiden = 66
- No-furosemiden = 56reference
- Outcome
- Intraoperative urinary oxygen tension (PuO₂), measured at four predefined time points
Methodological detailssingle-center, pilot
- Single-center
- Pilot
Main finding
As reported in the abstract
PuO₂ · 20 minutes after CPB initiation
P < 0.001
Observational data: associations, not effects.
Further findings
PuO₂ · before ICU transfer
P < 0.001
Postoperative creatinine, urine output, AKI (KDIGO) incidence and in-hospital mortality · index hospitalization
- Did not differ significantly between groups
Original publication
Pre‒Cardiopulmonary Bypass Furosemide Administration and Intraoperative Urinary Oxygen Tension During Coronary Artery Bypass Surgery: A Prospective Observational Study. J Cardiothorac Vasc Anesth. Published 30 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →