Respiratory failure & ventilation

Predicting ICU Mortality in Acute Respiratory Distress Syndrome Patients Using Machine Learning: The Predicting Outcome and STratifiCation of severity in Acute Respiratory Distress Syndrome (ARDS) (POSTCARDS) Study*

Crit Care MedPublished Prediction model development, testing and external validation study

Authors' conclusion

Both machine learning and traditional methods lead to promising models to predict ICU death in moderate/severe ARDS patients.

Study context

Population
Patients with moderate-to-severe ARDS managed with lung-protective ventilation in multidisciplinary ICUs1,000 development/testing, 303 validation
Participants
1,303 patients
Comparison
Machine learning vs logistic regression models
Outcome
Discrimination for ICU mortality (development and testing)
Methodological detailsfour prospective, multicenter, observational cohorts, machine learning (genetic algorithm, random forest, extreme gradient boosting)
  • Four prospective, multicenter, observational cohorts
  • Machine learning (genetic algorithm, random forest, extreme gradient boosting)

Performance

As reported in the abstract

Machine learning performance similar to logistic regression; AUC

0.87

95% CI 0.82–0.91

Further findings

External validation (independent cohort, n = 303)

Model performance similar to logistic regression model; AUC
0.91 (95% CI, 0.87-0.94)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Predicting ICU Mortality in Acute Respiratory Distress Syndrome Patients Using Machine Learning: The Predicting Outcome and STratifiCation of severity in ARDS (POSTCARDS) Study*. Crit Care Med. Published 31 August 2023. doi:10.1097/ccm.0000000000006030

Composed by AI from the published abstract and checked against it. How Briefs are made →

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