Cardiothoracic & vascular anesthesia
Predicting intraoperative hypoxemia in lung resection surgery: assessing the utility of oxygen reserve index measurements during one-lung ventilation before pleural opening
Authors' conclusion
In patients receiving OLV during lung surgery, ORI values and their changes measured during preemptive OLV before pleural opening can predict intraoperative hypoxemia.
Study context
- Population
- Adults undergoing lung resection surgery in lateral position with preemptive one-lung ventilation (OLV) (tidal volume 5 mL/kg, fraction of inspired oxygen (FiO2) 60%) for ≥5 min before pleural opening, tertiary medical center, January–April 2024
- Participants
- 113 adults
- Comparison
- Oxygen Reserve Index (ORI) at 5 min vs Change in ORI
- Outcome
- Prediction of intraoperative hypoxemia (SaO2 ≤ 90%)
Methodological detailssingle tertiary medical center, ROC curve analysis, DeLong's test
- Single tertiary medical center
- ROC curve analysis
- DeLong's test
Performance
As reported in the abstract
Prediction of intraoperative hypoxemia
| Test or model | AUC | Optimal cut-off |
|---|---|---|
| ORI at 5 min | 0.955 (95% CI: 0.899-1.000) | 0.040 |
| Change in ORI | 0.966 (95% CI: 0.935-0.997) | 0.110 |
AUC
ORI at 5 min0.955 (95% CI: 0.899-1.000)
Change in ORI0.966 (95% CI: 0.935-0.997)
Optimal cut-off
ORI at 5 min0.040
Change in ORI0.110
- Intraoperative hypoxemia incidence
- 13 (11.5%)
Original publication
Predicting intraoperative hypoxemia in lung resection surgery: assessing the utility of oxygen reserve index measurements during one-lung ventilation before pleural opening. J Clin Monit Comput. Published 26 February 2025. doi:10.
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