Respiratory failure & ventilation

Predicting mortality in severe Covid-19 Pneumonia: the role of right ventricular dysfunction

J Clin Monit ComputPublished Retrospective cohort study

Authors' conclusion

An increase in the RV basal diameter and the presence of ACP measured by TTE are independent predictors of in-hospital mortality in patients with C-ARDS.

Study context

Population
ICU patients with ARDS due to COVID-19 pneumonia (C-ARDS) on mechanical ventilation assessed by transthoracic echocardiography, Sanatorio de Los Arcos, Buenos Aires, Argentina, March 2020–January 2022
Participants
114 patients
Outcome
In-hospital mortality (RV echocardiographic variables as independent predictors)
Methodological detailsobservational, single-centre
  • Observational
  • Single-centre

Main finding

As reported in the abstract

Independent predictors of in-hospital mortality (multivariate logistic regression)
Odds ratio (95% CI)
RV basal diameter
3.16(1.36–7.32)
Presence of ACP
3.64(1.05–12.65)

Observational data: associations, not effects.

Further findings

Prevalence of right ventricle (RV) abnormalities on echocardiography

RV dilation (RV basal diameter >41 mm)
12.3%
No RV dilation
87.7%
Acute cor pulmonale (RV dilation with paradoxical septal motion)
6.1%
RV systolic dysfunction (qualitative evaluation)
7%

Original publication

Predicting mortality in severe Covid-19 Pneumonia: the role of right ventricular dysfunction. J Clin Monit Comput. Published 18 October 2023. doi:10.1007/s10877-023-01092-4

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