Respiratory failure & ventilation
Predicting outcomes in patients with exacerbation of COPD requiring mechanical ventilation
Authors' conclusion
Beyond predicting in-ICU mortality, the NIVO-score is a reliable tool in predicting 1-year mortality and NIV failure in AECOPD.
Study context
- Population
- Patients hospitalized for Acute exacerbations of COPD (AECOPD) requiring mechanical ventilation, January 1st, 2018 to December 31st, 2022of 302 ICU admissions
- Participants
- 190 patients
- Exposure
- Noninvasive Ventilation Outcomes (NIVO) score for predicting 1-year mortality and NIV failure
- Outcome
- Performance of the NIVO score in predicting 1-year mortality and NIV failure (intubation or death without intubation)
- Follow-up
- 1 year
Main finding
As reported in the abstract
Prediction of 1-year mortality and NIV failure
NIVO score
- AUC, 1-year mortality
- 0.68
- AUC, NIV failure
- 0.85
NIVO score
AUC, 1-year mortality0.68
AUC, NIV failure0.85
NIVO score over 7Hazard ratio (CI)
1-year mortality
4.4(1.8–10.9)
NIV failure
41.6(5.6–307.9)
Observational data: associations, not effects.
Further findings
Observed outcomes (cohort)
- Died in ICU
- 44 (23%)
- Failed NIV
- 62 out of 184 (34%)
- Died within 1 year of admission
- 78 (41%)
Characteristics of ICU death or NIV failure
- More severe COPD and more impaired blood gas parameters at admission
Original publication
Predicting outcomes in patients with exacerbation of COPD requiring mechanical ventilation. Ann Intensive Care. Published 20 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →