Cardiothoracic & vascular anesthesia
Preoperative Glycocalyx Status and Postoperative Organ Failure After Cardiac Surgery in the GLYPOCS Observational Cohort Study
Authors' conclusion
Preoperative glycocalyx thickness, evaluated using PBR, was not associated with postoperative complications. Reduced preoperative microvascular flow was independently associated with early postoperative complications after cardiac surgery.
Study context
- Population
- Patients undergoing cardiac surgery, December 2020 to August 2023
- Participants
- 119 patients
- Exposure
- Preoperative sublingual glycocalyx and microcirculation status vs postoperative complications
- Outcome
- Organ failure
- Follow-up
- 48 hours postoperatively
Methodological detailssingle-centre, observational
- Single-centre
- Observational
Main finding
As reported in the abstract
Early complications (organ failure within 48 h)
Early complications occurred (AKI, KDIGO ≥ 2, most frequent)
53.8%
Preoperative microvascular flow decreased in patients with early complications, aOR per µm/s
0.9957
p = 0.01
Observational data: associations, not effects.
Secondary outcomes
- Decreased microvascular flow and capillary density significantly associated with AKI and respiratory failure
Original publication
Preoperative Glycocalyx Status and Postoperative Organ Failure After Cardiac Surgery in the GLYPOCS Observational Cohort Study. J Cardiothorac Vasc Anesth. Published 21 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →