Cardiothoracic & vascular anesthesia
Preoperative Lung Function Assessment and the Impact of Spirometry Misdiagnosis on Mortality Following Cardiac Surgery
Authors' conclusion
A significant proportion of patients undergoing cardiac surgery have obstructive spirometry, many of whom have no diagnosis of respiratory disease. Mis- or undiagnosed obstructive disease may impact in-hospital mortality.
Study context
- Population
- Consecutive patients undergoing preoperative spirometry before cardiac surgery, single tertiary cardiothoracic teaching hospital, January 2010–September 2020
- Participants
- 16,906 consecutive patients
- Exposure
- Spirometric obstruction and respiratory diagnosis categories
- Diagnosis+/obstruction-n = 568
- Diagnosis-/obstruction+n = 3,672
- Outcome
- In-hospital mortality
Methodological detailsobservational, noncontrolled, single-centre
- Observational
- Noncontrolled
- Single-centre
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Documented history of lung disease
- Documented history of lung disease
- 3,284 (19.4%)
Obstruction on spirometry
- Obstruction on spirometry, overall
- 4,712 (27.9%)
- Obstructive spirometry without a respiratory diagnosis
- 3,672 (21.7%)
- COPD diagnosis without obstruction on spirometry
- 568 (39.2%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Preoperative Lung Function Assessment and the Impact of Spirometry Misdiagnosis on Mortality Following Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 21 May 2026. doi:10. 1053/ j. jvca. 2026. 05. 042
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