Cardiothoracic & vascular anesthesia

Preoperative Lung Function Assessment and the Impact of Spirometry Misdiagnosis on Mortality Following Cardiac Surgery

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

A significant proportion of patients undergoing cardiac surgery have obstructive spirometry, many of whom have no diagnosis of respiratory disease. Mis- or undiagnosed obstructive disease may impact in-hospital mortality.

Study context

Population
Consecutive patients undergoing preoperative spirometry before cardiac surgery, single tertiary cardiothoracic teaching hospital, January 2010–September 2020
Participants
16,906 consecutive patients
Exposure
Spirometric obstruction and respiratory diagnosis categories
  • Diagnosis+/obstruction-n = 568
  • Diagnosis-/obstruction+n = 3,672
Outcome
In-hospital mortality
Methodological detailsobservational, noncontrolled, single-centre
  • Observational
  • Noncontrolled
  • Single-centre

Main finding

As reported in the abstract

Observational data: associations, not effects.

Further findings

Documented history of lung disease

Documented history of lung disease
3,284 (19.4%)

Obstruction on spirometry

Obstruction on spirometry, overall
4,712 (27.9%)
Obstructive spirometry without a respiratory diagnosis
3,672 (21.7%)
COPD diagnosis without obstruction on spirometry
568 (39.2%)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Preoperative Lung Function Assessment and the Impact of Spirometry Misdiagnosis on Mortality Following Cardiac Surgery. J Cardiothorac Vasc Anesth. Published 21 May 2026. doi:10.1053/j.jvca.2026.05.042

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