Cardiothoracic & vascular anesthesia

Preoperative Ultrasound-Guided Internal Branch Block of Superior Laryngeal Nerve Reduces Postoperative Sore Throat Caused by Double Lumen Endotracheal Intubation: A Randomized Trial

Anesth AnalgPublished Randomised controlled trial

Primary result · Incidence of POSTResult — go to the resultEstimate 0.29 95% CI 0.10–0.81

Authors' conclusion

Preoperative US-guided iSLNB could significantly ameliorate the incidence and severity of POST induced by double-lumen bronchial catheter intubation.

Study context

Population
Patients undergoing thoracoscopic resection of pulmonary nodules/lobes/segments with one-lung ventilation (OLV) under general anesthesia (GA) and double-lumen tube intubation
Participants
82 patients
Comparison
Preoperative bilateral US-guided iSLNB plus GA vs GA alone
  • Sn = 41
  • Cn = 41reference
Primary endpoint
Incidence of POST
Follow-up
6 hours after surgery

Primary result

As reported in the abstract

Estimate

0.29

95% CI 0.10–0.81

P = 0.012

Events by treatment group

S

7 of 41

7 of 41

C

17 of 41

17 of 41

Further findings

OutcomeSCEstimateP value
Overall accumulated incidence of POST9/4120/410.30 (95% CI 0.11–0.77)P = 0.011
Incidence and severity of POST · 2 hours after surgeryIncidence P = .008; severity P = .0049/4120/410.30 (95% CI 0.11–0.77)P = 0.008

Incidence and severity of postoperative sore throat (POST) · 24 hours after surgery

Nonsignificant difference between groups

Incidence and severity of hoarseness · 2, 6, and 24 hours after surgery

Comparable between the 2 groups

Original publication

Preoperative Ultrasound-Guided Internal Branch Block of Superior Laryngeal Nerve Reduces Postoperative Sore Throat Caused by Double Lumen Endotracheal Intubation: A Randomized Trial. Anesth Analg. Published 25 May 2023. doi:10.1213/ane.0000000000006534

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