Cardiothoracic & vascular anesthesia

Prevalence and Characteristics of Persistent Postoperative Pain After Thoracic Surgery: A Systematic Review and Meta-Analysis

Anesth AnalgPublished Systematic review and meta-analysis

Authors' conclusion

One in 3 thoracic surgery patients developed PPP.

Study context

Population
Patients after thoracic surgery
Participants
19,001 patients · 90 studies
Outcome
Prevalence of persistent (≥3 months) postoperative pain (PPP)
Follow-up
Median 12 months
Methodological detailsrandom-effects meta-analysis, Medline, Embase and CINAHL searched from inception to May 1, 2022
  • Random-effects meta-analysis
  • Medline, Embase and CINAHL searched from inception to May 1, 2022

Pooled result

As reported in the abstract

Pooled overall prevalence of PPP · median follow-up 12 months

Pooled overall prevalence of PPP

38.1%

95% CI 34.1–42.3

Further pooled results

Characteristics of PPP among patients with PPP

Moderate-to-severe PPP (rating scale ≥4/10)
40.6% (95% CI, 34.4-47.2)
Severe PPP (rating scale ≥7/10)
10.1% (95% CI, 6.8-14.8)
Opioid analgesic use required
56.5% (95% CI, 44.3-67.9)
Neuropathic component
33.0% (95% CI, 22.5-44.3)

Original publication

Prevalence and Characteristics of Persistent Postoperative Pain After Thoracic Surgery: A Systematic Review and Meta-Analysis. Anesth Analg. Published 16 June 2023. doi:10.1213/ane.0000000000006452

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